Otc CBD Oil

Results of a study presented in a poster presentation during ASHP Midyear collected data of the available OTC CBD products being sold in Colorado pharmacies. Otc CBD Oil Head Office Crawford Pharmacy Crystal City Pharmacy Empire Pharmacy Galveston Specialty Pharmacy Harding & Parker Pharmacy Laurel Heights Pharmacy Liberty Drugs Lifecare Garza

OTC CBD Products Currently Available in Pharmacies

With recent surges in popularity, FDA guidance, and state legislation within the landscape of cannabis-derived compounds, pharmacies are increasingly supplying cannabidiol (CBD) products.

Of note, CBD is only 1 of the compounds found within the cannabis plant and has no psychoactive effects; delta-9-tetrahydrocannabidiol (THC) is a different compound that does produce psychoactive effects, and marijuana is a type of cannabis plant that possesses multiple naturally occurring compounds, including CBD and THC. 1

Study investigators Leticia Shea, PharmD, BCACP, Anna Carnazzo, PharmD candidate, and Janelle Matura, PharmD candidate, from the Rueckert-Hartman College for Health Professions at Regis University in Denver, Colorado, documented the OTC products currently being offered by pharmacies across Colorado. The findings were presented in a poster during the Association of Health-System Pharmacists (ASHP) 2020 Midyear Clinical Meeting and Exhibition.

Although there are myriad CBD products marketed and sold with medical claims, there is currently only 1 CBD product that has been evaluated and approved by the FDA for safety and efficacy. 1

As the CBD sphere of influence expands, pharmacists should “recognize the discrepancy between these CBD products and CBD approved by the FDA,” the researchers wrote. Importantly, pharmacists should also be prepared to effectively counsel patients on the use of untested CBD products that are available in their stores. 2

Of the 35 pharmacies included in the study, 18 (51%) sold at least 1 CBD product. Investigators took inventory of the CBD products at the 18 chain and independent pharmacies across the state of Colorado, located in both urban and rural regions. A total of 60 CBD products were recorded.

The majority of products took the form of oral drops/pumps, balms/salves, or creams/ointments. Other CBD product forms included topical oils, bath products, gummies, lotions, patches, and pet salves and balms.

Depending on the product form – oral, topicals, or transdermal – concentrations of compounds varied. In oral products, CBD concentrations varied from 10 to 60 mg/mL, with 13 (87%) labeled as “full spectrum” and therefore likely contained active cannabinoids other than CBD. In topical products, concentration ranged from 30 mg CBD/15 mL to 1000 mg CBD. Most topical products also contained other ingredients; among these products, 32% contained menthol, 17% contained camphor, 10% willow bark extract, and 10% contained peppermint, among other ingredients. The single transdermal product offered a 20mg CBD/24h dose, according to researchers.

Researchers reported that additional studies are needed to determine the safety and efficacy of these products in regard to the formulations themselves, as well as dosing.

“The impact of drug-interactions for topically applied CBD is currently unknown as no studies have evaluated [only CBD] topical formulations in humans,” investigators wrote. “The OTC CBD market is growing, and will be important for pharmacists to be cognizant of the variety of products being sold.”

CBD products are everywhere. But do they work?

By now, you’ve probably run into a product containing cannabidiol, also known as CBD. It’s in everything from drinks and pet products to lotions and chewable gummies. Even major drugstore chains have announced they will start carrying CBD products in certain states.

But many people still don’t really know what CBD is. Is it marijuana? Is it legal? Does it actually work? Is it safe?

The answers to those questions aren’t necessarily straight­forward. The only thing that is clear at this point: The marketing has gone way ahead of the science and the law when it comes to CBD products.

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That said, CBD is thought to be a safe and effective option for certain conditions. Below, we sort through the confusion by answering some of the most common questions about CBD.

Is CBD marijuana?

Yes and no. Cannabidiol is one of the two best-known active compounds derived from the marijuana plant. The other is tetrahydrocannabinol, or THC, which is the substance that that produces the “high” from marijuana.

CBD does not get you high, but the idea that it’s not psychoactive is something of a misconception in his opinion. It does change your consciousness. You may feel mellow, experience less pain, and be more comfortable. In addition, some CBD products do contain small amounts of THC.

While CBD can come from marijuana, it can also be derived from hemp. Hemp is a related plant with 0.3% or less of THC. This plant is often used to make fabrics and ropes. As of 2018, Congress made hemp legal in all 50 states, and consequently CBD derived from hemp is also legal. The rules around marijuana-derived CBD, however, are far less clear.

Is marijuana-derived CBD legal?

Again, yes and no, depending on where you live. In some states marijuana is legal for both recreational use and medical use. In other states, it’s legal only for medical use. And in some areas, it’s not legal at all.

When it comes to CBD products, the FDA is still trying to get its arms around the issue. The agency is just starting the process of hashing out some rules regarding CBD sales. Officials recently formed a working group to create guidelines that could allow companies to legally market CBD products. Currently, CBD products are considered supplements, which aren’t FDA-regulated, and it is illegal for companies to make health or therapeutic claims about the products in their marketing. In announcing its effort to set CBD marketing rules, the FDA also signaled that it is cracking down on CBD companies that are using “egregious and unfounded claims” to market their products to “vulnerable populations.”

Currently, there is only one CBD product that has FDA approval: a prescription medication called Epidiolex, used to treat some rare severe seizure disorders in children. The bottom line is that in order to understand whether CBD is legal where you live, you’ll need to consult your state health department website or professionals in your community.

Does CBD work?

Yes, there is evidence that CBD works for some conditions, but certainly not all the conditions it is being promoted for these days. There’s no evidence, for example, that CBD cures cancer. There is moderate evidence that CBD can improve sleep disorders, fibromyalgia pain, muscle spasticity related to multiple sclerosis, and anxiety.

People report that oral CBD helps relieve anxiety and pain and also leads to better sleep. However, the same may not be true for a host of other CBD products on the market today, in particular those that are rubbed on the skin. It’s hard to know whether these have any clinical benefit, because they haven’t been tested sufficiently.

Testing also shows that many products don’t contain what’s claimed on the label. For example, they may have less CBD than advertised. So, buyer beware.

Where should you purchase CBD products?

If you are interested in trying a CBD product, it’s best to seek one through a dispensary, which is an establishment legally licensed to sell marijuana, if they are available in your state. Dispensary products must be labeled so you can see exactly how much CBD is in the product and whether it also contains THC. A small amount of THC in a CBD product isn’t typically problematic. But larger amounts could cause a “high” and may present a risk if you are going to drive.

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Also, keep in mind that CBD products aren’t standardized and will vary. It helps to keep a journal recording what type of CBD product you took, how much, and your response to it. This will help you track what works and what doesn’t for your condition.

Is CBD safe?

The safest way to take CBD is orally, as a tablet, chewable, or tincture (a concentrated liquid typically administered with a dropper). Steer clear of any illegally sold synthetic CBD products, sometimes called “spice” or “bath salts.” These products have induced psychotic reactions in some people and pose a major health risk.

For adults, CBD appears to be a very safe product. CBD does produce side effects for some people, including nausea, fatigue, and irritability. It may also interact with certain medications, so always check with your doctor before use.

But for children under age 21 it’s a different story. It’s also not clear if any amount of CBD is appropriate for children.

Evidence regarding CBD is still building. Now that some states have legalized recreational and medical use of marijuana products, including CBD, scientists are finding it easier to conduct research. More will be known in the next 5 to 10 years, including whether there are yet undiscovered problems associated with long-term use.

Image: Vanessa Numes/Getty Images

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Otc CBD Oil

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OTC Products / CBD Oil

CBD or cannabidiol is a promising phytocannabinoid that works within the endocannabinoid system. Agricultural hemp contains the CBD . It has been recognized for its benefits on human and animal health because it is capable of affecting nearly every biological process. This page is for informational purposes only. In Ohio, CBD Oil must be purchased through a licensed dispensary with a medical marijuana card. The History of Cannabis Cannabis has been around for a long, long time. Western medicine was introduced to cannabis in the 1840s. Despite the current use and status of cannabis in the United States, cannabis was the medicine of choice in the early 1900s because it was promoted as having analgesic, sedative, anti-inflammatory, antispasmodic, and anticonvulsant properties. Become Familiar with the Terminology Cannabis Sativa L is the source of medical cannabis and agricultural hemp.

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Cannabis Sativa L. contains over 120 cannabinoids, including CBD. Medical Cannabis is cannabis for medical purposes. Agricultural or Industrial Hemp is less than 0.3% TCH by dry weight. This hemp uses the whole plant which has added benefits. The Endocannabinoid System In the mid 1900s, we learned that we have our own endocannabinoid system. In addition, we learned that we have our own cannabis like compounds inside of our body naturally. The endocannabinoid receptor was first discovered in 1992. Since that time, scientists and researchers have been studying the central regulatory system called the endocannabinoid system or the ECS. Naturally occurring cannabis-like compounds and enzymes influence this system.

The ECS or endocannabinoid system is a very important system. The endocannabinoid system is responsible for creating and maintaining homeostasis within the body. The body contains endocannabinoids and receptors everywhere. In addition, every organ system contains these receptors. In different tissues and different parts of the body, cannabinoids perform different tasks. Despite this, the goal of the cannabinoids is always the same: homeostasis. Homeostasis is maintaining a stable internal environment despite fluctuations in the external environment. Especially relevant is how the endocannabinoid system is involved in the direct regulation of appetite, metabolic health, pain/inflammation, thermoregulation, intraocular pressure, sensation, muscle control, motivation/reward, mood and memory. In addition, the endocannabinoid system is involved in learning and synaptic plasticity.

Maintaining Endocannabinoid System Tone

The CB1 receptor within the endocannabinoid system is responsible for decreasing anxiety, reducing pain, decreasing inflammation, controlling sensory perception, memory and cognitive function. Opposite this, a diet filled with toxins and processed foods along with stress will overstimulate the CB1 receptor. As a result of this over stimulation, the body has bad side effects: anxiety, inflammation, insulin resistance, poor sleep, etc.

CBD Oil Working Inside the Endocannabinoid System

CBD oil is a phytocannabinoid that can mimic endocannabinoids. This allows the CBD oil to modulate the tone of the endocannabinoid system. Modulating the tone of the ECS promotes homeostasis inside the body. The ECS is essential to life. The Cannabis Sativa L plant contains the CBD. Because of this, CBD oil belongs to a class of molecules called cannabinoids. CBD oil is a legal dietary supplement. In addition, nutrient rich hemp contains excellent nutritional value and essential fatty acids. Lastly, CBD oil is not psycho active; it will not get you high. Inside the endocannabinoid system, CBD balances the consistent over stimulation of the CB1 receptor. Cannabidiol or CBD helps balance the system that keeps you balanced.

CBD Safety

Studies show that CBD is non-toxic. In addition, chronic use and high doses up to 1500mg per day of CBD are reportedly well tolerated in humans. Nor does CBD use affect GI transit nor alter psychomotor or psycholgic functions.

What is the Research ?

Cannabis is a schedule 1 drug. Hence, it is very difficult to conduct research. By definition, schedule 1 means that there is no potential for medical benefit and highly addictive. When a drug is listed as schedule 1, you are limited to the amount of research that can be done on humans. There is no reference of CBD in the federal acts. Furthermore, CBD is not directly scheduled. Also, hemp is not defined as “marijuana” under the Controlled Substance Act. Lastly, Agricultural hemp fiber, stalk seed and oils can be lawfully imported into the United States and these portions of the hemp plant may enter into US commerce.