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GW Pharmaceuticals is undertaking a major research programme in the UK to develop and market distinct cannabis-based prescription medicines [THC:CBD, High THC, High CBD] in a range of medical conditions. The cannabis for this programme is grown in a secret location in the UK. It is expected that the product will be marketed in the US in late 2003. GW’s cannabis-based products include selected phytocannabinoids from cannabis plants, including D9 tetrahydrocannabinol (THC) and cannabidiol (CBD). The company is investigating their use in three delivery systems, including sublingual spray, sublingual tablet and inhaled (but not smoked) dosage forms. The technology is protected by patent applications. Four different formulations are currently being investigated, including High THC, THC:CBD (narrow ratio), THC:CBD (broad ratio) and High CBD. GW is also developing a specialist security technology that will be incorporated in all its drug delivery systems. This technology allows for the recording and remote monitoring of patient usage to prevent any potential abuse of its cannabis-based medicines. GW plans to enter into agreements with other companies following phase III development, to secure the best commercialisation terms for its cannabis-based medicines. In June 2003, GW announced that exclusive commercialisation rights for the drug in the UK had been licensed to Bayer AG. The drug will be marketed under the Sativex brand name. This agreement also provides Bayer with an option to expand their license to include the European Union and certain world markets. GW was granted a clinical trial exemption certificate by the Medicines Control Agency to conduct clinical studies with cannabis-based medicines in the UK. The exemption includes investigations in the relief of pain of neurological origin and defects of neurological function in the following indications: multiple sclerosis (MS), spinal cord injury, peripheral nerve injury, central nervous system damage, neuroinvasive cancer, dystonias, cerebral vascular accident and spina bifida, as well as for the relief of pain and inflammation in rheumatoid arthritis and also pain relief in brachial plexus injury. The UK Government stated that it would be willing to amend the Misuse of Drugs Act 1971 to permit the introduction of a cannabis-based medicine. GW stated in its 2002 Annual Report that it was currently conducting five phase III trials of its cannabis derivatives, including a double-blind, placebo-controlled trial with a sublingual spray containing High THC in more than 100 patients with cancer pain in the UK. Also included is a phase III trial of THC:CBD (narrow ratio) being conducted in patients with severe pain due to brachial plexus injury, as are two more phase III trials of THC:CBD (narrow ratio) targeting spasticity and bladder dysfunction in multiple sclerosis patients. Another phase III trial of THC:CBD (narrow ratio) in patients with spinal cord injury is also being conducted. Results from the trials are expected during 2003. Three additional trials are also in the early stages of planning. These trials include a phase I trial of THC:CBD (broad ratio) in patients with inflammatory bowel disease, a phase I trial of High CBD in patients with psychotic disorders such as schizophrenia, and a preclinical trial of High CBD in various CNS disorders (including epilepsy, stroke and head injury). GW Pharmaceuticals submitted an application for approval of cannabis-based medicines to UK regulatory authorities in March 2003. Originally GW hoped to market cannabis-based prescription medicines by 2004, but is now planning for a launch in the UK towards the end of 2003. Several trials for GW’s cannabis derivatives have also been completed, including four randomised, double-blind, placebo-controlled phase III clinical trials conducted in the UK. The trials were initiated by GW in April 2002, to investigate the use of a sublingual spray containing THC:CBD (narrow ratio) in the following medical conditions: pain in spinal cord injury, pain and sleep in MS and spinal cord injury, neuropathic pain in MS and general neuropathic pain (presented as allodynia). Results from these trials show that THC:CBD (narrow ratio) caused statistically significant reductions in neuropathic pain in patients with MS and other conditions. In addition, improvements in other MS symptoms were observed as well. Phase II studies of THC:CBD (narrow ratio) have also been completed in patients with MS, spinal cord injury, neuropathic pain and a small number of patients with peripheral neuropathy secondary to diabetes mellitus or AIDS. A phase II trial of THC:CBD (broad ratio) has also been completed in a small number of patients with rheumatoid arthritis, as has a trial of High CBD in patients with neurogenic symptoms. A phase II trial has also been evaluated with High THC in small numbers of patients for the treatment of perioperative pain. The phase II trials provided positive results and confirmed an excellent safety profile for cannabis-based medicines. GW Pharmaceuticals received an IND approval to commence phase II clinical trials in Canada in patients with chronic pain, multiple sclerosis and spinal cord injury in 2002. Following meetings with the US FDA, Drug Enforcement Agency (DEA), the Office for National Drug Control Policy, and National Institute for Drug Abuse, GW was granted an import license from the DEA and has imported its first cannabis extracts into the US. Preclinical research with these extracts in the US is ongoing.

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Am I right, Blanche? After Joshette finished telling the story, he shop cbd oil for sleep turned to Blanche. What s the matter with you, it s rude gw pharmaceuticals cbd gummies oil for sale to barge in cbd gummy without saying kushly cbd gummies ceo hello! Lux pouted.

This is the young master of the Sen Lan family in Gw Pharmaceuticals Cbd Oil For Sale front of him! I also counted on the steward to save myself with the 100 mg thc free cbd gummies power of the Weichen family.

The rapid development has dragged down the economy of their territory, it turns out that all the money in his hand was used to buy soldiers, no wonder the economy will be dragged down.

City Totem, Wind lion: If the totem is inlaid in any position in the city, the totem will summon the wind lion clan and become the totem guardian beast of the weed gummies city, When we arrived at the scene, the place was already full of gw pharmaceuticals cbd oil for sale people, and there was a lot of uproar and noise.

Here, here, all belong to good cheap cbd gummies our Huaxia collar, other areas, you can assign them at will, I have no opinion.

The tall young man still has some understanding of magic energy communication technology, but it is precisely because of this understanding that he questioned the authenticity of the mobile phone.

The eldest son and the gummies eldest grandson have the online shop cbd oil right of inheritance gummies supplements in the first place in the same can cbd gummies help depression generation as soon as they are born, Looking at the finalized new law in his hand, he nodded with gw pharmaceuticals cbd oil for sale satisfaction, This new law may still be a little does cbd help anxiety imperfect, but with the continuous revision of the law thc gummies court, it will definitely be improved step by step.

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Tell me, why aren t we allowed to ride horses in the town? This is the order of the Lord.

After sneaking into the city of Saint Zell, the boss and Chu looked for the black currant seed oil side effects direction cbd oil benefits and went directly to the lord s mansion in the center, After the old man finished speaking, gw pharmaceuticals cbd oil for sale he hurriedly stepped aside, If he continued to chatter and angered the Third Highness, it seemed that he would not even have a place to reason.

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I think he must have encountered some fortuitous encounter, a treasure of heaven and earth.

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Beside the third prince, the old man who presided over the selection ceremony saw his eyes lit up and his expression was excited. The City Lord s Mansion was actually the idea of the Sen Lan gw pharmaceuticals cbd oil for sale family and grandfather Yarman.

That sword just now cbd gummies for parkinsons consumed one-third of his vindictive energy! That is to say, in the heyday, only three who owns kushly cbd oil swords can be used.

It just doesn t make sense! Director Tris slapped the table and said angrily.

Madara and Itachi are extremely powerful ninjas, and they are extremely relieved to hand over the Tianmu Pavilion of the capital to them, He really didn t need to go to Nice gw pharmaceuticals cbd oil cbd gummies for sale a day earlier and spend the night in Nice.

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Lei best of sale gummies mg cbd gummies Kuang took a step forward, trying to block this vindictive qi, but was stopped by reaching out his hand, letting the dou qi wrap himself tightly.

Take pure cbd oil anger on both of us, After all, capturing the sword was cbd gummies near 85015 only Locke s personal decision, and speaking of it, Blanche is still your savior, can you fly with cbd oil in carry on Master, The gw pharmaceuticals cbd oil for sale tip of the gun stopped on Hardy s throat again, exactly the same as the previous position.

Because the host s territory was upgraded to a cbd oil for eczema forum large territory, cbd quit smoking gw pharmaceuticals cbd oil for sale gummy the system began to automatically upgrade.

Aside, Charles asked, Weed picked up tablets cbd gummies for anxiety a mobile phone, opened the back cover, and revealed a magic stone (magic source stone) that was cut into squares.

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Rutgers looked at Kret and asked for Kret s opinion, Kret opened his half-closed eyes, revealing an cbd gummies 15 mg unusually cold gaze, staring at Sidney and Harangos.

OK to reselect! Seeing that there were only ten seconds left in the countdown, he hurriedly spoke.

Such a tired march is an extremely dangerous thing, Once 1000mg of cbd the enemy takes the initiative to attack, the consequences will be disastrous. On the side, the big housekeeper Rutgers stared at the magic communication device in Benedict s gw pharmaceuticals cbd oil for sale hand with envious eyes, wishing he had one in his hand.

Seeing the others pizza sydney cbd gummies coming in, Adelaide hurriedly greeted him: Master, Master.

Shaking his head: No, Indeed not, if he has not left the capital, the most lord system will not be activated, I am afraid that he is still a poor person who has been neglected.

The spear pierced through the boss s chest and emerged from his back, The Scarlet General held his spear high, and the boss was put on the spear by him, cannabis gummies like a prawn pierced by a bamboo skewer, Hot Products, gw pharmaceuticals cbd oil for sale Speaking of mobile phones, the sales of mobile phones are already very hot now.

The powerful defense of the empty cbd oil and gout sand barrier was directly torn apart by the two sharp arrows, and continued to charge towards Gaara and Azir.

Must gw pharmaceuticals cbd oil for sale reviews not be, Recently, he has not had time gummy to practice in the lord s mansion, but he has been arranging trusted subordinates to practice in the lord s mansion, and now Tie San and others have risen to the fifth level.

After the boss left, Benedict asked Rutgers, Rutgers, can you see the strength of this boss. But how difficult is it to understand the law? The twelfth-level powerhouse of dr oz cbd gummies countless gw pharmaceuticals cbd oil gummies products for sale geniuses is stuck at this step and cannot step into the legend for life.

Lord Right Prime Minister let cbd gummies ok for high blood pressure the Chinese leader settle in the fortress, It can be seen that in the heart of the right Prime Minister, the status of the Chinese leader is no less than these.

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She s dead, she s dead! After Levi said, the room was silent, except for the Alcott family, everyone looked at Levi with angry eyes.

With a swoosh, under the acceleration of the law of the wind system, the sharp arrow shot towards Chesterton like lightning. If there benefits of cbd are so many lords colluding with the Shadow Eagle, the lords gw pharmaceuticals cbd oil for sale in the Nice City area will not believe it.

Next, was the handover ceremony fab cbd oil of the city masters of Benedict and Alvin, When the ceremony was held, the weather was calm and there were no accidents.

This is the first legendary creature in Huaxia, although Thor can t be too far from the city, it can only be used for defense.

Said, he would not be like a stunned young man, and he agreed without asking what the City Lord s cbd gummies products Mansion asked for. Early the next morning, just as gw pharmaceuticals cbd oil for sale they had just finished breakfast and were about to leave the city of Gallia and continue to move towards the capital, the courtyard door was suddenly knocked.

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A breath of death came out gw pharmaceuticals cbd oil for sale from the body, making people feel fearful at a glance, Judging gw pharmaceuticals cbd oil for sale from cbd gummy for inflammation the fact that they killed each other and killed two companions, there will never be more than five sacred fruits in the valley, otherwise there is no need for gw pharmaceuticals cbd oil for sale them to turn against each other and kill each other.

s young master, cbd cbd drink oil in olive oil The most exaggerated thing is that there were nearly twenty maids and nearly a hundred guards standing around the carriage, which made him have to sigh which young master this is.

Joshette said, Master, this sacred fruit belongs to you, just please let me and Blanche leave, not because shark tank best cbd gummies of Locke s affairs.

Actually, I don t know cbd oil boise much about this Sky Curtain organization, Having said natures boost royal cbd gummies reviews that, he selectively told Arman and Bowen about the situation of Tianmu. What made Swain more uncomfortable than the gw pharmaceuticals cbd oil for sale decline in strength was the death of the evil crow.

It only has the strength cheef botanicals cbd gummies review of the peak of the fifth level or the early stage of the sixth level, and the seventh-level powerhouse can easily defeat it.

After do hemp hearts have cbd gummies the Right Prime Minister arrests himself, he will definitely be put in prison, and there will be a chance at that time.

I want to say more about the old best cbd for anxiety man here, Miss Blanche used the wind in her last arrow, Okay, who s next? asked, Next, gw pharmaceuticals cbd oil for sale the heroes each chose the skin they wanted.

After all, golden goat cbd gummies review such a powerful organization appeared out of thin air, which is too strange.

There are not many such geniuses on the mainland, and there is not a single one who has become gw pharmaceuticals cbd oil for sale a legendary powerhouse.

Fourth, you will be responsible for dealing with the City Lord s Mansion in the future, This kind gw pharmaceuticals cbd oil for sale of task is simply to let the soldiers led by Huaxia go to their deaths and sacrifice in vain.

Except for Ignas, all the people atorvastatin and cbd oil of the Alcott family were silent, for fear of venting their anger on them and suffering unwarranted disasters.

After Swain s shape health gummies change was over, the cbd side effects evil crow made two long, happy sounds.

Out of desperation, the underground race had to send troops to help the Blue Shirts again. On the city wall of Leibao painless cbd oil Fortress, Thomas, and other city lords and lords of the gw pharmaceuticals cbd oil for sale big city stood on the city wall and watched the performance of the two little dragons and the magicians on their backs.

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The giant sword slashed Steven s left arm, Immediately, Steven s left arm began to shrink at a speed visible to the naked eye, and the flesh and blood was devoured by the giant sword in Locke s hand.

Seeing the students in the audience who were indignant and noisy because they were not college students, they raised their index fingers and made a shush gesture around their mouths, The gw pharmaceuticals cbd oil for sale next summon requires 200,000 gold coins, and there are not many gold coins on the body.

OK to cbd for sleep reselect! gw pharmaceuticals cbd oil for sale Gritting his teeth, If you can t select satisfactory auxiliary gummy gush elements this time, you can only choose to accept your fate.

Also, Claren said, help me contact the Tianmu organization, I want to gw pharmaceuticals cbd oil for sale phat hempies cbd gummies see them, preferably at the top.

Just when they were gummies delicious stunned, the two shurikens in the boss s hands had already been shot. Aside from the system summoning, they are no different gw pharmaceuticals cbd oil for sale from ordinary humans.

Could there be a family recruiting cbd gummies that stop alcohol cravings the two of them? After the battle, the old man asked.

Mickey smiled when he heard the words: After all, it is someone who is especially concerned by the snack merchants, and it is not ashamed for your apprentice to lose to him.

Unfortunately, this time, you chose the wrong object! I ll results edible gummies give you a chance to compensate me with one million gold coins and make a public apology. Lord Lord, you haven t named this city yet, Swain reminded, gw pharmaceuticals cbd oil for sale Can t always refer to this city as an underground city, right.