CBD Oil For Inflammatory Pain Dosage

Learn how CBD oil is used to reduce inflammation and can help treat arthritis, inflammatory bowel disease, and psoriasis. Find out CBD dosage information and learn how to talk to your doctor about CBD oil as an anti-inflammatory supplement. CBD is one of the most promising natural remedies to come along in years. Along with having the ability to potentially alleviate ailments like depression, Thinking of using CBD products? We can help you determine how much to take for anxiety and pain relief.

Inflammation and CBD Oil: Benefits, Effectiveness, and Dosage

One of the most discussed benefits of cannabidiol (CBD) oil is its ability to fight inflammation. These anti-inflammatory properties may be why CBD oil has been found to help with inflammatory conditions as wide-ranging as Alzheimer’s disease to irritable bowel syndrome to multiple sclerosis, and chronic pain.

Below, you’ll find information on how CBD oil can help manage and even treat a number of inflammation-related conditions and diseases. With this information, you and your doctor can then decide if CBD oil could be a helpful addition to your medical regimen.

Benefits of Taking CBD Oil For Inflammation

If you’re finding it difficult to function on your current inflammation treatment plan, it might be time to look elsewhere. CBD oil has the potential to not only reduce symptoms, but can also reduce the overall inflammation in your body, boosting your health and vitality.

When dealing with inflammation, you might typically turn to medications like ibuprofen and aspirin. But long-term use of these non-steroidal anti-inflammatory drugs (NSAIDs) can produce negative side effects, including kidney disease and peptic ulcers.

In contrast, CBD oil can offer anti-inflammatory results without these side effects.

CBD oil does not present any obvious side effects, but it does have the potential to interact with some medications you may be taking like antibiotics or antidepressants. So, before you even consider taking CBD oil for inflammation, you should consult with your physician or health care professional.

Don’t be afraid to talk to your doctor about CBD oil as an option for inflammation. The more open and honest you can be, the more likely you’ll be to find a solution that works for you. You can’t get answers to your questions if you do not ask them.

Effectiveness of CBD Oil to Reduce Inflammation

To understand how effective CBD oil is at reducing inflammation, you need to know a little bit about the science behind how CBD interacts with your body.

The endocannabinoid system (ECS) in the human body produces and responds to cannabinoids, which play a key role in healthy body function and inflammation reduction. The cannabis plant produces phytocannabinoids like CBD, which are similar to the endocannabinoids produced by the human body; both types of cannabinoids interact with the ECS.

Two cannabinoid receptors, type 1 (CB1) and type 2 (CB2), are the most significant when it comes to CBD.

CB1 receptors are found primarily in the brain while CB2 receptors are located throughout the body and central nervous system. CB2 receptors help regulate the immune system, and in doing so, regulate inflammatory responses. In fact, chronic inflammation has been shown to play a significant role in the development and progression of many diseases, indicating that normal CB2 function is not only crucial for reducing inflammation, but also for staying generally healthy.

CBD has been found to bind to some CB2 receptors, but it mainly exerts its effects through indirect activation of non-cannabinoid receptors. CBD acts on these receptors to target mechanisms and processes in the body that cause inflammation.

Cytokines, for example, are small proteins released by immune cells when the body is under some type of stress. Certain cytokines are involved in the initiation and continuation of inflammation. CBD oil has been shown to disrupt this immune response, preventing inflammation from occurring in the first place.

Another way CBD oil is known to fight inflammation is in relation to the neurotransmitter adenosine. CBD acts as an adenosine reuptake inhibitor, meaning it helps to increase the amount of adenosine in the brain, which in turn impacts adenosine receptors. Activation of these receptors, particularly the A2A receptor, plays a significant role in reducing inflammation in the body.

CBD Oil for Inflammation of the Joints

Conditions like arthritis and lupus are related to the activity of the immune system and cause inflammation, which can be incredibly disruptive, causing a great deal of pain in the joints and limiting mobility. These autoimmune disorders prevent the immune system from being able to recognize the body’s natural processes, causing it to attack and destroy healthy cells and tissues.

CBD oil is an immune suppressor, meaning it can potentially reduce or eliminate detrimental, inflammatory responses.

Current testing indicates a lot of potential for CBD oil as a viable treatment for arthritis pain and inflammation, without any “evident side effects.”

CBD Oil for Inflammation in the Digestive Tract

Chronic inflammation in the digestive tract can lead to conditions like ulcerative colitis and Crohn’s disease. Collectively known as inflammatory bowel disease (IBD), these conditions can cause diarrhea, abdominal pain, fatigue, and weight loss. The exact cause of IBD is unknown, but it’s believed that just like other forms of inflammation, an abnormal immune response leads to an inflammatory attack on healthy cells in the digestive tract.

Early studies on cannabis and management of IBD symptoms have produced positive results, but more research is still needed to definitively say whether CBD oil is a sure-fire remedy for inflammation in the digestive tract.

CBD Oil for Inflammation of the Skin

Inflammation does not just have an impact on your body’s internal functions, but can also impact the appearance and condition of your skin.

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Acne appears when hair follicles become clogged by oil, dead skin cells, and bacteria and can be triggered by stress, diet, medications, and hormones. Because CBD oil is anti-inflammatory, it can reduce the inflamed appearance of acne when applied topically (e.g. in lotion) and when ingested. More than just reducing the appearance of puffy skin, CBD oil’s effects on the ECS can inhibit excess oil production, keeping your pores from getting clogged, and preventing the occurrence of acne flare-ups.

Psoriasis is another autoimmune disorder, and is characterized by an overproduction of immature skin cells triggered by an abnormal immune response. Individuals with psoriasis often experience itchiness, redness, swelling, and inflammation; some sufferers may also develop psoriatic arthritis which leads to painful inflammation in the joints.

There is no cure for psoriasis and many of the traditional treatments carry harmful side effects like numbness, headaches, and high blood pressure, or simply lose their effectiveness over time. CBD oil can reduce the growth of keratinocytes, or immature skin cells, decreasing the size, appearance, and irritation of psoriasis patches. And as discussed above, CBD oil helps suppress a number of abnormal immune responses, effectively reducing inflammation without causing negative side effects.

How to Take CBD Oil for Inflammation

As the research indicates, CBD oil has tremendous potential for providing relief for inflammation, inflammatory diseases , and even chronic pain .

So, if you’ve spoken to your doctor and are ready to try CBD oil as a treatment, you have a variety of options when it comes to getting CBD into your system; a few of these include drops, vapes, sprays, shatter, and even gummies. CBD oil drops under the tongue and vapes will likely provide the fastest and most potent effects, but ingesting CBD oil via edibles may produce a different, longer-lasting outcome that you may find to be more pleasurable. Try out a few different methods to see which is best for you.

Again, before you start using CBD oil for inflammation, it is best to consult with your physician or healthcare provider. You might also consider consulting with a cannabis doctor who has extensive knowledge specific to CBD oil as a medical treatment.

Because no two people are the same, there is no standard dosage of CBD oil for inflammation, but start by following the recommended serving size on a CBD product.

If you’re still having trouble finding a dosage recommendation, we here at CBD Oil Review have tested hundreds of products to come up with a standard, starting dosage for you to try:

The CBD Oil Review Serving Standard is 25 mg of CBD, taken twice daily.

If you are not getting results from this amount, we recommend increasing the serving size by 25 mg every 3 to 4 weeks until you find relief.

What are the best CBD oils for inflammation?

Once you have consulted your physician or a cannabis doctor and decided to try CBD oil for inflammation, you are going to want to find a product that best suits you and your personal needs.

To start, reference our CBD oil Brand Reviews , and look for companies with all five badges.

CBD Dosage for Inflammation

CBD is one of the most promising natural remedies to come along in years. Along with having the ability to potentially alleviate ailments like depression, insomnia, and epilepsy, CBD has also shown effectiveness in reducing inflammation.

If you’re trying to self-medicate with CBD to help with your inflammation, this article is for you. Here we define CBD, present where the research rests at the moment, and explain how to find the right amount for you.

Table of Contents

What is CBD?

CBD stands for cannabidiol, one of many hundreds of active compounds present in the cannabis plant. These compounds, called cannabinoids, are responsible for all of the lovely things cannabis does to us, from relaxing us to easing afflictions like inflammation.

In contrast to its party-hardy cousin THC, CBD does not get you high. What it does do is make you feel good in plenty of other ways.

But what does the research say about CBD and your health?

The Current Research on CBD

There are lots of discussions centered around CBD today. Research is heavily underway to determine what it treats, how much of it to take, and whether there are any potential long-term effects to be aware of.

CBD and Inflammation

In 2016, an animal study showed that CBD reduced joint inflammation in lab rats by reducing their joint swelling. Additionally, the study showed no notable side effects. In fact, most studies of CBD for inflammation have been on animals — however, the results are looking promising for humans.

A 2017 study indicated the anti-inflammatory properties of CBD could help with conditions like inflammatory bowel diseases, cardiovascular diseases, multiple sclerosis, Alzheimer’s, and other inflammatory conditions.

CBD and Safety

In 2017, researchers found that studies on CBD generally indicated a high level of safety. Another conclusion of this study was that different people require different dosages of CBD to achieve the optimum response. The range of doses can be quite wide.

Make sure to talk to your doctor before starting CBD. It could be the case that CBD isn’t right for you or that it could interact with another medication you’re taking. CBD interacts with your body through the endocannabinoid system — basically, a complex set of receptors that affect things like mood, heart rate, anxiety, and more — so it’s really important to check with a healthcare professional before starting CBD.

How to Find the Right Dosage for Your Inflammation

Several factors come into play in determining your ideal dosage:

  • Your weight
  • Your body’s response to CBD
  • The bioavailability of the type of CBD you choose
  • Your condition
  • The concentration of your CBD
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Assuming your doctor hasn’t recommended a CBD dosage for you, the best way to begin is to start with a small dosage and work your way up. Start with either 20 or 40 mg per day, increasing by 5 mg each week until you start to notice a change in your inflammation. Keep track of this so you can find your optimum dose.

Dosage Calculations

When you’re calculating dosage, keep in mind that different types of products have different bioavailabilities. Bioavailability means how much of the substance actually makes it to your bloodstream. The following are some general bioavailability numbers:

  • Topical CBD:
  • CBD edibles (like gummies) and capsules: 5-15%
  • CBD oil drops: 30%
  • CBD vapes: >50%

In other words, 300 mg of CBD in an edible may only yield you 45 mg maximum, while CBD oil drops could yield nearly 100 mg.

Look at the product’s packaging. It should tell you how much is in a single serving. It’s particularly important to be able to calculate the dosage for CBD oil, as this is a common form of taking CBD.

A CBD oil bottle should deliver 1 mL per dropper, which may contain a stated amount of CBD. But how much is a single drop of the oil?

Consider that a single drop is usually around 0.05 mL of oil. If your 10-mL bottle contains 1,500 mg of CBD, that means there’s roughly 7.5 mg of CBD per drop.


CBD is natural, and research is showing it’s safe. If you’re trying to find the right dosage for your inflammation, try starting with 20 or 40 mg per day and increasing by increments of 5 mg each week. When you start to notice results, stay at that dosage!

Our dosing calculator will also help you understand how to find a great starting dosage.

How Much CBD Should You Take? Here’s How to Find Your Perfect Dose

Thinking of using CBD products? We can help you determine how much to take for anxiety and pain relief.

Taylor Leamey writes about all things wellness. She holds a bachelor’s degree in both Psychology and Sociology and is a certified sleep coach.

CBD products are everywhere — gas stations, grocery stores and standalone storefronts. And they’re not going anywhere. What was once considered a trend, is now a legitimate option for pain and anxiety relief .

If you’re interested in adding CBD products to your lifestyle, you’ve probably got a lot of questions about things like dosage and form. However, you should know that there aren’t federal oversights or regulations for CBD products. Up to 70% of CBD products you buy on the internet either have more or less CBD than listed on the label. Determining how much you should take can be tricky. Here’s what you need to know before buying CBD products for anxiety and pain relief.

What can you use CBD for?

Research, though limited, indicates that CBD has legitimate health benefits. While there is no FDA regulation, research has shown that full-spectrum and broad-spectrum CBD effectively treat pain and anxiety. There’s only one FDA-approved CBD product, called Epidiolex, that’s available by prescription. Epidiolex treats seizure disorders such as Lennox-Gastaut syndrome and Dravet syndrome.

However, there are several other benefits and uses of CBD products.

The most common uses of CBD

  • To lessen symptoms of anxiety and depression for things like muscle pain or migraines
  • To reduce chemotherapy-induced nausea
  • Relieve inflammatory diseases
  • Help with behavioral symptoms of dementia or Alzheimer’s disease
  • Managing multiple sclerosis and improving mobility

The CBD market is continuously expanding with new products. However, there are four main types of CBD product categories. All of which will vary in potency and dosage per unit.

Oils and tinctures

CBD oils generally come in either a liquid or capsule form. You can take the extracts independently or use the dropper to add them to food or drinks. Liquid tinctures are usually taken directly under the tongue.

“Tinctures are generally taken at higher concentrations than oils. This means that if you were taking 1 milliliter of tincture, you would need to drop the concentration down to 0.5 milliliters. A good rule of thumb is to start with a small dose (0.25 milliliters) and slowly increase your dose over time,” says Reda Elmardi, a registered dietician and certified nutritionist.


Edible CBD products are quickly becoming very popular, likely because of their convenience and flavor profiles. With edibles, you have several options in flavor, potency and prices. They have everything, from gummies to cookies, chocolates and even granola bars.


CBD is also available in topical creams and salves applied directly to the skin. Popular forms are lotions, creams or ointments. Topical CBD products are good options for muscle pains, joint inflammation or nerve pain.

Topical CBD is one of the more difficult forms for determining dosage. Not only does potency vary by product, but also varies by how much you use each application. It’s important to follow manufacturer instructions carefully.

How to determine the best CBD dosage for you

CBD products express dosage in milligrams. Epidiolex starts with a dosage of 2.5 milligrams taken twice a day. After a week, you can increase the dosage to 5 milligrams twice a day. Federal regulation makes determining dosage straightforward.

For the rest of the products on the market not regulated by the FDA, there are no established guidelines for CBD concentration, which makes determining how much you should take a little more difficult. There are a few key factors you need to keep in mind — your weight, what you’re treating and the concentration of the product.

The ideal dosage for you will vary depending on what you’re using it for and what form you’re taking. Don’t forget that different forms also mean how quickly it takes effect. Generally, edibles, oils and capsules will take roughly 30 to 60 minutes to take effect. Smoking or vaping CBD will bring it on significantly quicker since the CBD absorbs into your bloodstream rather than your digestive system.

CBD dosage will vary by condition

In general, the CBD dosage is dependent on the disease and its ability to be managed by CBD. The research that is available on CBD treatments has very varied dosage levels. Clinical studies have varied in oral doses from 100 to 800 milligrams a day. Others administer lower levels around 40 milligrams. A 2019 study investigating CBD for anxiety found that 300 to 600 milligrams reduced anxiety symptoms. However, that study was limited to 57 adult males.

“For generalized anxiety or sleep disorders, 25 to 75 milligrams per day is recommended, while for PTSD, 33 to 50 milligrams per day is recommended. In severe anxiety, a patient’s dose might be increased to 300 to 600 milligrams. If the patient is experiencing pain due to chemotherapy, 50 to 60 milligrams is recommended, with a maximum daily dose of 600 milligrams,” says Kimberly Langdon, a board-certified MD.

How much CBD is best for you will depend on your body. Your body weight and existing medications will influence the ideal dosage for you.

Can you take too much CBD?

A clinical review of studies confirmed that people tolerate doses as high as 1,500 milligrams a day. We want to stress that the research around CBD dosage is still really young, so there is not much to point to about how much is too much for people. More research is needed to definitively conclude the ideal dosage for each condition.

Not a ton of known side effects associated with CBD products. Though fatigue, diarrhea and appetite changes have been reported. The FDA states that CBD can cause liver damage and potentially impact the other prescription medications you’re taking.

If you’re starting your CBD journey, it’s best to slowly build your dosage so you can monitor how it affects you.

“The idea is to start very low (i.e., 5 milligrams per use) and increase daily usage by 5 milligrams every two days until you start feeling results. Then, stop increasing and keep using the same number of milligrams or drops. For many people, the amount that provides modest benefits in the first couple days will, after consistent use, provide more and more benefit over time,” says Dr. Dustin Sulak, an integrative physician and leading cannabis clinician.

How to calculate CBD dosage

For some forms of CBD, determining how much is each unit is simple. Capsules or gummies tend to have an expressed milligram content, making dosage much easier than oils or creams.

Oils or tinctures with a dropper bottle list the CBD content for the total liquid bottle. So instead of eating a gummy that’s 50 milligrams, it will look more like 7,500 milligrams of CBD in the 30-milliliter bottle. Some bottles will offer serving sizes — like one drop — to indicate dosage. This allows you to have greater control over how much you are intaking, but even still, it’s not a perfect science.

Some bottles with a traditional nutrition label on the back will tell you exactly how much is in one dropper. If you are unsure, it’s a good idea to reach out to the company to find out. It can be difficult to figure out how much you’re intaking for the bottles that do not break down by serving size and offer only the total amount. It is difficult, but not impossible; it just takes a little bit of math.

Say you have a 30-milliliter bottle of CBD oil, and each drop is 0.05 milliliters.

To determine how many milligrams of CBD per milliliter, you divide the total milligram content by how much the bottle is. In this example, the math would look like this:

7,500 milligrams divided by 30 milliliters = 250 milliliters.

There is 250 milligrams of CBD per milliliter for this product. Next, you want to know exactly how much CBD is in each drop.

250 milliliters x 0.05 milliliters = 12.5 milliliters per drop.

This calculation works with any bottle of CBD. Once you know how much CBD is in each drop, you can accurately take your ideal amount. “To ensure the best results, keep track of how much you take, how many times a day you take it and rate your symptoms daily (by rating 1 to 10, 10 being best) to see if they are getting better or worse,” Sulak advises.

Too long, didn’t read?

CBD is a continually evolving field in both products and research. While research is lacking, what is available suggests that CBD does have therapeutic benefits and is generally very well tolerated by people. Still, more research is needed to really dig into the long-term side effects and best dosage markers for the average person.

In place of federal regulations, use your best judgment regarding how much CBD you are taking. Talking to your doctor about dosage is always a good idea when in doubt.

The information contained in this article is for educational and informational purposes only and is not intended as health or medical advice. Always consult a physician or other qualified health provider regarding any questions you may have about a medical condition or health objectives.

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